Excitatory amino acid receptors.

Excitatory amino acid receptors in schizophrenia.

Growing evidence suggests an involvement of excitatory amino acid (EAA) systems in schizophrenia. Precedent exists for changes in binding to kainate, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, N-methyl-D-aspartate subtypes of EAA receptors. Current evidence indicates that in schizophrenia, EAA receptor levels can be decreased, unchanged, or even increased in certain brain regions...

Ii. Role of Excitatory Amino Acid Receptors in Seizures

Excitatory Amino Acid Transmission

This book represents the proceedings of a Satellite Symposium to the 30th Congress of the International Union of Physiological Sciences, held in Canada during July of 1986. It is the twenty-fourth volume of the neurology and neurobiology collection. The contents of the book are divided into seven sections, beginning with an overview of the field of excitatory amino acid transmission, and a disc...

Excitatory amino acid neurotransmission.

In recent years great progress has been made in understanding the function of ionotropic and metabotropic glutamate receptors; their pharmacology and potential therapeutic applications. It should be stressed that there are already N-methyl-D-aspartate (NMDA) antagonists in clinical use, such as memantine, which proves the feasibility of their therapeutic potential. It seems unlikely that compet...

Excitatory amino acid antagonists and epilepsy.

I06 (1990) Eur. J. Pharmacol. 189, 381-391 18. Honor&, T., Lauridsen, J. and Krogsgaard-Larsen, P. (1082) J. Neurochem. 38,173-178 19. Murphy, L). E., Snowhill, E. W. and Williams, M. (1087) Neurochem. Kes. 12,775-782 20. Lund, T. M., Madsen, U., Ebert, H.. Jsrgensen, I;. S. and Krogsgaard-Ia-sen, 1’. (1991) Med. Chem. Kes. 1, 130-141 21. Hansen, J. J., Lauridsen, J., Nielsen, E., and Krogsgaar...